From published airline schedules as of 4 September 2026, cross-checked against award availability in 26 airline mileage programs, San Diego has nonstop service to 12 international and 76 domestic destinations. Pairs the programs sell only with a connection are left out.
See all direct flights in United States →Business class flights to San Diego →
12 nonstop destinations
76 nonstop destinations
SAN
Who actually operates the nonstops, from published airline schedules as of 4 September 2026— ranked by the number of destinations each airline serves without a stop from SAN. Pick an airline for its full list; each destination below names its carriers.