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Flights to and from Knoxville: 30 Nonstop Destinations

30 nonstop destinations from Knoxville, United States

Knoxville (TYS)

From published airline schedules as of 3 August 2026, cross-checked against award availability in 26 airline mileage programs, Knoxville has nonstop service to 0 international and 30 domestic destinations. Pairs the programs sell only with a connection are left out.

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International

0 nonstop destinations

Domestic

30 nonstop destinations

Airports

TYS

Airlines Flying Nonstop from Knoxville

Who actually operates the nonstops, from published airline schedules as of 3 August 2026— ranked by the number of destinations each airline serves without a stop from TYS. Pick an airline for its full list; each destination below names its carriers.

Allegiant Aireconomy only16 nonstop destinationsSouthwest Airlineseconomy only8 nonstop destinationsAmerican Airlines6 nonstop destinationsUnited Airlines5 nonstop destinationsDelta Air Lines4 nonstop destinations
Frontier Airlineseconomy only1 nonstop destination

Domestic Destinations from Knoxville

AtlantaATLDelta Air LinesAustinAUSAllegiant Air (economy), Southwest Airlines (economy)BaltimoreBWISouthwest Airlines (economy)BostonBOSAllegiant Air (economy)CharlotteCLTAmerican AirlinesChicagoMDWAllegiant Air (economy)ChicagoORDAmerican Airlines, United AirlinesDallasDALSouthwest Airlines (economy)DallasDFWAmerican AirlinesDenverDENAllegiant Air (economy), Frontier Airlines (economy) +2DetroitDTWDelta Air LinesFort LauderdaleFLLAllegiant Air (economy)HoustonHOUAllegiant Air (economy)HoustonIAHUnited AirlinesJacksonvilleJAXAllegiant Air (economy)Key WestEYWAllegiant Air (economy)Las VegasLASAllegiant Air (economy), Southwest Airlines (economy)MiamiMIAAmerican AirlinesMinneapolisMSPDelta Air LinesNashvilleBNASouthwest Airlines (economy)New YorkEWRAllegiant Air (economy), United AirlinesNew YorkLGADelta Air LinesOrlandoMCOAllegiant Air (economy), Southwest Airlines (economy)PhiladelphiaPHLAllegiant Air (economy), American AirlinesPhoenixPHXAllegiant Air (economy)SarasotaSRQAllegiant Air (economy)TampaTPASouthwest Airlines (economy)ValparaisoVPSAllegiant Air (economy)WashingtonDCAAmerican AirlinesWashington, D.C.IADAllegiant Air (economy), United Airlines

Knoxville Nonstop Flights: Questions Answered

As of 3 August 2026, 6 airlines operate scheduled nonstop flights from Knoxville (TYS). Ranked by nonstop destinations, the busiest are Allegiant Air (16 destinations, economy only), Southwest Airlines (8, economy only), American Airlines (6), United Airlines (5) and Delta Air Lines (4).
Knoxville has scheduled nonstop service to 30 destinations as of 3 August 2026: 0 international and 30 domestic, from TYS.

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Knoxville
Knoxville (TYS)• United States
TYS