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Flights to and from Knoxville (TYS): 30 Nonstop Destinations

McGhee Tyson Airport, Knoxville, United States · nonstop from 16 cities

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International

0 nonstop destinations

Domestic

30 nonstop destinations

Nonstop service from

16 cities

Airlines Flying Nonstop from TYS

Who actually operates the nonstops from Knoxville, from published airline schedules as of 3 August 2026— ranked by the number of destinations each airline serves without a stop. Pick an airline for its full list from the city; each destination below names its carriers.

Allegiant Aireconomy only16 nonstop destinationsSouthwest Airlineseconomy only8 nonstop destinationsAmerican Airlines6 nonstop destinationsUnited Airlines5 nonstop destinationsDelta Air Lines4 nonstop destinations
Frontier Airlineseconomy only1 nonstop destination

Domestic Destinations from TYS

AtlantaATLDelta Air LinesAustinAUSAllegiant Air (economy), Southwest Airlines (economy)BaltimoreBWISouthwest Airlines (economy)BostonBOSAllegiant Air (economy)CharlotteCLTAmerican AirlinesChicagoMDWAllegiant Air (economy)ChicagoORDAmerican Airlines, United AirlinesDallasDALSouthwest Airlines (economy)DallasDFWAmerican AirlinesDenverDENAllegiant Air (economy), Frontier Airlines (economy) +2DetroitDTWDelta Air LinesFort LauderdaleFLLAllegiant Air (economy)HoustonHOUAllegiant Air (economy)HoustonIAHUnited AirlinesJacksonvilleJAXAllegiant Air (economy)Key WestEYWAllegiant Air (economy)Las VegasLASAllegiant Air (economy), Southwest Airlines (economy)MiamiMIAAmerican AirlinesMinneapolisMSPDelta Air LinesNashvilleBNASouthwest Airlines (economy)New YorkEWRAllegiant Air (economy), United AirlinesNew YorkLGADelta Air LinesOrlandoMCOAllegiant Air (economy), Southwest Airlines (economy)PhiladelphiaPHLAllegiant Air (economy), American AirlinesPhoenixPHXAllegiant Air (economy)SarasotaSRQAllegiant Air (economy)TampaTPASouthwest Airlines (economy)ValparaisoVPSAllegiant Air (economy)WashingtonDCAAmerican AirlinesWashington, D.C.IADAllegiant Air (economy), United Airlines

Fly Nonstop to Knoxville (TYS) From

AtlantaATLDelta Air LinesBentonvilleXNABirminghamBHMCharlotteCLTAmerican AirlinesChicagoORDAmerican Airlines, United AirlinesDallasDFWAmerican AirlinesDenverDENAllegiant Air (economy), Frontier Airlines (economy) +2DetroitDTWHoustonIAHUnited AirlinesMiamiMIAAmerican AirlinesMinneapolisMSPDelta Air LinesNew YorkLGADelta Air LinesPhiladelphiaPHLTampaTPAWashingtonDCAWashington, D.C.IADAllegiant Air (economy), United Airlines

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Knoxville
McGhee Tyson Airport• United States
TYS