All direct flights from Knoxville
Southwest Airlines Nonstop Flights from Knoxville: 8 Destinations
0 international and 8 domestic destinations without a stop from TYS
Every destination Southwest Airlines serves nonstop from Knoxville, United States, from published airline schedules as of 3 August 2026. Seasonal and not-yet-launched services are marked; connections are not listed. Southwest Airlines sells economy only — no business or first class cabin.
International
0 nonstop destinations
Domestic
8 nonstop destinations
Airports
TYS
Southwest Airlines Domestic Destinations from Knoxville
Other Airlines Flying Nonstop from Knoxville
Every other airline with scheduled nonstops from TYS, ranked by the number of destinations it serves without a stop. Pick one to see its full list.
Southwest Airlines Nonstop Flights from Other Cities
The other cities we track Southwest Airlines nonstops from, busiest first.
Denver, United States93Chicago, United States83Baltimore, United States77Las Vegas, United States77Phoenix, United States60St. Louis, United States54San Diego, United States47Kansas City, United States44Sacramento, United States32Los Angeles, United States30Fort Lauderdale, United States29Indianapolis, United States25Oakland, United States24New Orleans, United States22Pittsburgh, United States22San Antonio, United States21Milwaukee, United States20Atlanta, United States19Burbank, United States18Cancun, Mexico18Miami, United States18Albuquerque, United States16Long Beach, United States16Seattle, United States16Raleigh-durham, United States15Buffalo, United States14Portland, United States14Louisville, United States13San Francisco, United States13Minneapolis, United States12Oklahoma City, United States12Ontario, United States12Panama City, United States12Reno, United States12Boston, United States11San Juan, Puerto Rico11Santa Ana, United States11New York, United States10San Jose, United States10Puerto Vallarta, Mexico9Tucson, United States9Grand Rapids, United States8Jacksonville, United States8Savannah, United States8Charlotte, United States6Manchester NH, United States5Rochester, United States5Santa Rosa, United States5
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